**UPDATE: 6 Hospitalized, 2 Seriously Injured in Mission District Crash**

UPDATE: A dramatic car crash in the Mission District of San Francisco has left six people hospitalized, including two pedestrians with life-threatening injuries. The incident occurred on Friday afternoon at the intersection of 22nd Street and South Van Ness Avenue, prompting an urgent response from local police and fire officials.

According to authorities, two pedestrians were struck while crossing the street, suffering severe injuries that required immediate transport to San Francisco General Hospital. Fire Department Assistant Chief Bill Storti confirmed that in addition to the two critically injured pedestrians, four others sustained minor injuries when the car collided with another vehicle.

Witnesses reported chaotic scenes as emergency services arrived. One resident, Amerie Wheeler, described hearing screeching brakes followed by a “big crash” and frantic calls for help. “I saw two people lying on the street. One was conscious and asking about the other,” Wheeler recounted, emphasizing the emotional toll of the incident.

The area has been cordoned off with police tape, with debris scattered across the road, including shoes and clothing from the victims. As emergency personnel worked, one individual from the vehicle that struck the pedestrians was seen being loaded into a neck brace, highlighting the severity of the situation.

Officials are investigating the circumstances surrounding the crash, with early reports suggesting that both pedestrians could survive their injuries, according to Chief Storti. The community is urged to stay clear of the area while the investigation continues.

This incident serves as a stark reminder of the dangers pedestrians face in urban environments. As details emerge, residents are encouraged to remain vigilant and report any further developments.

Stay tuned for updates as authorities continue to assess the situation and provide further information on the victims’ conditions. Your support for local journalism is vital; consider joining our community of readers to stay informed on critical news in the Mission District and beyond.